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Inequalities in Meningioma Survival: Results from the National Cancer Database

Background: Meningiomas are the second most common primary tumor of the central nervous system, with an incidence of approximately 30,000 new cases per year. However, there is a paucity of literature examining how healthcare, demographic, and socioeconomic factors impact patient survival outcomes.

Methods: We conducted a retrospective study of patients from the National Cancer Database (NCDB) diagnosed with meningioma between 2004 and 2012. Univariate and multivariate analysis was performed to investigate the impact of patient, tumor, and treatment factors on overall survival: age, comorbidities, tumor behavior and size, and treatment strategy.

Results: Diagnosis and treatment at an academic/research program, private insurance, female sex, Hispanic ethnicity, Asian race, higher median household income, and high school diploma conferred a survival advantage on both univariate and multivariate analyses of the 162,222 patients in the NCDB. Black race was associated with decreased survival on multivariate analysis.

Conclusions: Disparities in survival outcomes in patients with meningiomas exist across multiple healthcare, demographic, and socioeconomic factors. Additional research is needed to elucidate the genetic and environmental factors driving these inequalities.



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